SQSTM1/p62

2 papers

Animals1

Latest

3 in 12 months

Aging and Disease11 Oct

Lysosomal Competence in Skeletal Muscle Aging: Autophagic Flux, Measurement Gaps, and Human Translation

ReviewAutophagy

Autophagy18 Aug

Non-cell autonomous control of presynaptic remodeling by the hypothalamic autophagy-NPY axis

Experiments in fliesAutophagy

Autophagy20 May

FGF21 rejuvenates aged human adipose-derived mesenchymal stem cells via enhancement of TFE3-mediated autophagy flux

Experiments in ratsInterventions

Autophagy2 Oct

Aging-rewired metabolic cues promote autophagy and senescence via DRAM1

Experiments in miceAutophagy

Brain Research Bulletin5 Aug

Inhibition of Sirtuin 2 enhances autophagy and restores neuronal function in aged hippocampal neurons

Experiments in miceSirtuin signalling

Biochimica et Biophysica Acta Molecular Cell Research25 May

Oscillatory shear stress activates integrin β3, blocking autophagic flux in endothelial cells and promoting endothelial cells senescence

Experiments in animalsMechanisms

Aging Cell9 May

SQSTM1/p62 Orchestrates Skin Aging via USP7 Degradation

Study in peopleMechanisms

Aging Cell28 Apr

Age-Associated Decline in Autophagy Pathways in the Retinal Pigment Epithelium and Protective Effects of Topical Trehalose in Light-Induced Outer Retinal Degeneration in Mice

Experiments in animalsInterventions

Autophagy4 Mar

Autophagy regulates cellular senescence by mediating the degradation of CDKN1A/p21 and CDKN2A/p16 through SQSTM1/p62-mediated selective autophagy in myxomatous mitral valve degeneration

Experiments in human cellsAutophagy

GeroScience17 Jan

The anti-senescence effect of D-β-hydroxybutyrate in Hutchinson-Gilford progeria syndrome involves progerin clearance by the activation of the AMPK-mTOR-autophagy pathway

Experiments in cellsInterventions