Soluble CD40 ligand
2 papers2 findings
- Human trial1
- Humans1
Upstream
1LPA 18:0/18:1/20:4/22:6 and SPHINGOSINE-1-PHOSPHATE
mediatesin humans1
1 study
LPA 18:0/18:1/20:4/22:6 and SPHINGOSINE-1-PHOSPHATE
mediatesin humans1
LPA 18:0/18:1/20:4/22:6 and SPHINGOSINE-1-PHOSPHATE mediates soluble CD40 ligand in humans (12–32% of the heat–sCD40L association).
“LPA 18:0/18:1/20:4/22:6 and S1P mediated 12-32% of the heat-sCD40L association.”
Humansmediation of the heat–sCD40L associationn = 112
Journal of exposure science & environmental epidemiology16 Oct 2026
Associations
1Ambient temperature
upin humans1+304% higher
1 study
Ambient temperature
upin humans1+304% higher
Ambient temperature is associated with soluble CD40 ligand in humans (304% higher).
“along with sCD40L (304% higher)”
Humansheat exposure27.7 °C versus 18.7 °C cumulative temperature30 daysn = 112
Journal of exposure science & environmental epidemiology16 Oct 2026
Latest
1 in 12 monthsJournal of Exposure Science & Environmental Epidemiology
Association between ambient temperature and thrombosis-related signaling lipids: Implications for early cardiovascular risk
Cohort study of 112 peopleThrombosis