LPA 18:0/18:1/20:4/22:6 and SPHINGOSINE-1-PHOSPHATE

1 finding

Effects

Soluble CD40 ligand

mediatesin humans1

1 study

LPA 18:0/18:1/20:4/22:6 and SPHINGOSINE-1-PHOSPHATE mediates soluble CD40 ligand in humans (12–32% of the heat–sCD40L association).
“LPA 18:0/18:1/20:4/22:6 and S1P mediated 12-32% of the heat-sCD40L association.”
Humansmediation of the heat–sCD40L associationn = 112
Association between ambient temperature and thrombosis-related signaling lipids: Implications for early cardiovascular risk
Journal of exposure science & environmental epidemiology16 Oct 2026