snoRNA

Biomarker

2 papers study it29 more mention it

Human trial1
Cells1

Funding

1 grant since 2025

Dutch Research Council

Improving healthy ageing by manipulating snoRNA expression
Dutch Research CouncilUniversity Medical Center Groningen2025

Latest

5 papers in 12 months

Journal of Drug TargetingSep 18

Senescence-associated extracellular vesicles in skin aging and regeneration: from pathophysiology to therapeutic opportunities

ReviewCellular senescence

Paper

Frontiers in Cell and Developmental BiologyJul 14

Dual modes of action: direct regulation and ceRNA-mediated mechanisms of ncRNAs in dermal fibroblast senescence

ReviewCellular senescence

Paper

bioRxivApr 21

Pseudouridylation of rRNA by specific snoRNA disrupts ribosomal machinery and consequently affects metabolism, longevity and neurodegeneration

Preprint: experiments in fliesLipid and ceramide metabolism

Paper

Aging CellMar 31

A Cluster of Three snoRNAs Including Jouvence Required in the Gut Determines Lifespan and Confers Neuroprotection Through Metabolic Parameters

Experiments in fliesLipid and ceramide metabolism

Paper

AAIC 2025 AbstractDec 25

Synergies between Small RNA and Protein Biomarkers for Early Detection of Cognitive Impairment – results from EPAD

Cohort study of 1,913 peopleMild cognitive impairment

Paper

Journal of Thrombosis and HaemostasisMar 10

Red blood cell Rpl13a small noncoding nucleolar RNAs guides 2'-O-methylation on peroxidasin messenger RNA promoting venous thrombosis in aging

Cohort study in peopleMechanisms

Paper

Free Radical Biology & MedicineFeb 13

Rpl13a snoRNAs-regulated NADPH oxidase 1-dependent ROS generation: A novel RBC pathway mediating complement C3a deposition and triggering thrombosis in aging and venous blood clotting disorders

Study in peopleComplement system

Paper

Cell Communication and SignalingFeb 12

sdRNA-D43 derived from small nucleolar RNA snoRD43 improves chondrocyte senescence and osteoarthritis progression by negatively regulating PINK1/Parkin-mediated mitophagy pathway via dual-targeting NRF1 and WIPI2

Study of 3 peopleMitophagy

Paper

Mechanisms of Ageing and DevelopmentDec 23

Aberrant expression of messenger and small noncoding RNAomes in aged skin of rats

Experiments in ratsSkin

Paper

bioRxivNov 21

Searching for Jouvence SnoRNA in the Horse Genome

Preprint: computational studyMechanisms

Paper

snoRNA

Funding

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