miRNA
Biomarker2 papers2 findings
- Humans1
Associations
2MMSE
upin humans1
1 study
MMSE
upin humans1
miRNA is associated with MMSE in humans.
Humansplasma total EV-enriched fractions
Low-Sample Input miRNA Profiling in Extracellular Vesicles-Enriched Plasma Fractions from Older Adults With/out Cognitive Impairment · International journal of molecular sciences · 1 Sep 2026
Cognitive impairment
downin humans1
1 study
Cognitive impairment
downin humans1
Cognitive impairment is associated with miRNA in humans.
Humansage-related cognitive impairmentplasma total EV-enriched fractions
Low-Sample Input miRNA Profiling in Extracellular Vesicles-Enriched Plasma Fractions from Older Adults With/out Cognitive Impairment · International journal of molecular sciences · 1 Sep 2026
Funding
National Institute on AgingUS$883.2k2 grants since 2024
Latest
45Young-donor cell packages improved limb repair in rats
In a rat experiment, cell-released packages from young donors had stronger tissue-repair effects than those from older donors after blood supply was…In a rat experiment, cell-released packages from young donors had stronger tissue-repair effects than those from older donors after blood supply was restricted.
An Artificial Intelligence-Based Blood Test using protein and miRNA biomarkers for Colorectal Cancer Screening
Microglial depletion triggers distinct molecular responses in male and female aged mouse brains
Aged male mice showed far larger proteomic shifts than females following microglial removal, including alterations in synaptic and mitochondrial…Aged male mice showed far larger proteomic shifts than females following microglial removal, including alterations in synaptic and mitochondrial proteins.
Multi-omics analysis reveals molecular networks driving muscle decline in aging vervet monkeys
Researchers identified coordinated changes in DNA methylation, miRNAs, and gene expression distinguishing older female monkeys with slower gait from…Researchers identified coordinated changes in DNA methylation, miRNAs, and gene expression distinguishing older female monkeys with slower gait from middle-aged counterparts.
Extracellular vesicle microRNA promotes muscle regeneration by suppressing AP2M1
Delivering miR-193b-3p improved muscle repair in injured mice and targeted a protein elevated in sarcopenic human tissue.Delivering miR-193b-3p improved muscle repair in injured mice and targeted a protein elevated in sarcopenic human tissue.
Extracellular vesicles carrying two microRNAs reduce vascular aging markers in progeria cells
Vesicles from melatonin-treated stem cells targeted SRSF1 and SP1 to lower progerin and cellular prion protein in cell models.Vesicles from melatonin-treated stem cells targeted SRSF1 and SP1 to lower progerin and cellular prion protein in cell models.
Engineered exosome-mimetic nanoparticles improve liver function in aged mice
The synthetic particles deliver microRNAs and proteins to reduce senescence, lower fibrosis, and shift macrophages toward a pro-resolving state.The synthetic particles deliver microRNAs and proteins to reduce senescence, lower fibrosis, and shift macrophages toward a pro-resolving state.