Skeletal muscle transcriptome

Biomarker

1 paper studies it39 more mention it2 findings

  • Humans1

Associations

2

Testosterone

mixedin humans1

1 study
  1. Testosterone is associated with skeletal muscle transcriptome in humans.

    “Free, but not total, testosterone was strongly associated with the muscle transcriptome”

    Humanshealthy malesfree testosteroneskeletal musclemalesn = 81

    Free testosterone linked to muscle gene activity, not strength

    bioRxivPreprint

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VO2peak

mixedin humans1

1 study
  1. Skeletal muscle transcriptome is associated with VO2peak in humans (21 miRNAs and 1,744 genes).

    “Regression analyses identified 21 miRNAs and 1,744 genes significantly correlated with VO peak after adjusting for age and sex.”

    Humansskeletal musclen = 72

    MicroRNA Regulatory Targets Related to VO₂peak Decline in Older Adult Participants of the Study of Muscle, Mobility and Aging (SOMMA)

    bioRxiv : the preprint server for biologyPreprint

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Molecular Pain

Activity-limiting pain linked to muscle gene activity in older adults

A cross-sectional study of 742 adults aged 70 or older linked activity-limiting pain to muscle gene activity patterns that differed between men and women.A cross-sectional study of 742 adults aged 70 or older linked activity-limiting pain to muscle gene activity patterns that differed between men and women.

Cross-sectional · 742 peopleMuscle
bioRxiv

Free testosterone linked to muscle gene activity, not strength

In 81 healthy males aged 18–80, an observational study linked free testosterone to muscle gene activity, but not muscle mass or strength.In 81 healthy males aged 18–80, an observational study linked free testosterone to muscle gene activity, but not muscle mass or strength.

Preprint: cross-sectional · 81 peopleMuscle
Clinical Nutrition

Lysine breakdown linked to limb lean mass in humans

In 40 postmenopausal women, blood and muscle measurements suggested distinct changes rather than a uniform shift across the lysine breakdown pathway.In 40 postmenopausal women, blood and muscle measurements suggested distinct changes rather than a uniform shift across the lysine breakdown pathway.

Mendelian randomizationMechanisms