Serum creatine kinase activity

There are 3 papers on serum creatine kinase activity in aging research: 1 trial and 1 observational study in people, 1 in animals.

Biomarker

3 papers study it2 more mention it4 findings

1 new paper in 30 daysSee all 5 papers on serum creatine kinase activity

“The sCK level was not associated with the risk of ESRD.”
Low Serum Creatine Kinase Level Predicts Mortality in Patients with a Chronic Kidney DiseasePloS one2016doi:10.1371/journal.pone.0156433
  • Human trial1
  • Humans1
  • Animals1

Interventions

2

Swimming training

downin mice1

1 study
  1. Swimming training decreases serum creatine kinase activity in mice (glycerol-induced muscle injury).

    “Swimming training accelerated functional recovery (grip strength, rotarod endurance, gait mechanics) and reduced serum creatine kinase activity, indicating mitigated muscle damage.”

    Animalsglycerol-induced muscle injury

    Swimming Training Alters Immune Cell Spatiotemporal Distribution to Mitigate Fat Infiltration and Enhance Muscle Regeneration

    Phenomics (Cham, Switzerland)

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Creatine monohydrate plus conjugated linoleic acid

no changein humans1

1 study
  1. Creatine monohydrate plus conjugated linoleic acid showed no clear effect on serum creatine kinase activity in humans.

    “with no changes in serum CK activity or liver function tests”

    Human trialsix months

    Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults

    PloS one

More on Creatine monohydrate plus conjugated linoleic acid

Effects

1

End-stage renal disease

no changein humans1

1 study
  1. Serum creatine kinase activity was not clearly linked with end-stage renal disease in humans.

    “The sCK level was not associated with the risk of ESRD.”

    Humansmedian follow-up 6.0 years

    Low Serum Creatine Kinase Level Predicts Mortality in Patients with a Chronic Kidney Disease

    PloS one

More on End-stage renal disease

Associations

1

Prealbumin

upin humans1

1 study
  1. Serum creatine kinase activity is associated with prealbumin in humans (baseline cross-sectional comparison).

    “Higher sCK level at baseline was associated with a lower age, a higher body mass index, and a higher level of 24 h urinary creatinine excretion, serum albumin and prealbumin”

    Humansbaseline cross-sectional comparison

    Low Serum Creatine Kinase Level Predicts Mortality in Patients with a Chronic Kidney Disease

    PloS one

More on Prealbumin

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