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Biomarker

1 paper

  • Humans1

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1 grant since 2021

National Institute on AgingUS$1.7m

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Exploration

Bazi Bushen eased stress-induced signs of aging in mice

A 12-month chronic stress experiment in mice found that the compound medicine eased signs of aging and reduced inflammation across several tissues.A 12-month chronic stress experiment in mice found that the compound medicine eased signs of aging and reduced inflammation across several tissues.

Experiments in miceInterventions
Diabetologia

Genetic background shapes cell aging and diabetes in male mice

Male mice carrying the same diabetes-linked mutation developed diabetes on a mixed genetic background, but maintained normal blood sugar on another background.Male mice carrying the same diabetes-linked mutation developed diabetes on a mixed genetic background, but maintained normal blood sugar on another background.

Experiments in miceMechanisms
bioRxiv

RNA version patterns linked to age in adult human brains

An analysis of adult human brain RNA data found age-linked patterns in the mix of RNA versions that persisted after accounting for each gene’s total RNA amount.An analysis of adult human brain RNA data found age-linked patterns in the mix of RNA versions that persisted after accounting for each gene’s total RNA amount.

Preprint: computational studyAI & data
Journal of Advanced Research

Bile acid corrected abnormal fat-cell formation in human cells

Lab experiments in bone marrow cells from patients with postmenopausal osteoporosis also found reduced senescence, a state in which cells stop dividing.Lab experiments in bone marrow cells from patients with postmenopausal osteoporosis also found reduced senescence, a state in which cells stop dividing.

Experiments in miceInterventions
bioRxiv

Method maps cell ancestry and gene activity in human blood

The method paired gene activity and DNA-marking measurements at about 10,000 cells per sequencing library, a collection of prepared genetic material.The method paired gene activity and DNA-marking measurements at about 10,000 cells per sequencing library, a collection of prepared genetic material.

Preprint: cohort study of 21,000 peopleAI & data