Senescent cancer cells

2 papers study it33 more mention it

Animals1
Cells1

Latest

4 papers in 12 months

LifeMay 4

Postbiotics as Emerging Strategy Targeting Obesity- and Aging-Related Breast Cancer-Prospects in Prophylaxis and Therapy

ReviewBreast cancer

Aging CellMar 6

Decreased Glucose Metabolism and Declined Chaperones Are Unique Features Required for the Survival of Senescent Fibroblasts and Pyruvate Dehydrogenase Is a Potent Senolytic Target

Experiments in miceInterventions

ApoptosisFeb 10

Removing therapy-induced senescent cancer cells targets and potentiates the response of pancreatic cancer cells toward PARP inhibitors as maintenance therapy

Experiments in human cellsPancreatic cancer

Nature AgingJan 13

Senotoxins target senescence via lipid binding specificity, ion imbalance and lipidome remodeling

Experiments in miceInterventions

Journal of Medicinal ChemistryOct 20

Discovery of Novel PI3K/BRD4 Dual Inhibitors for Esophageal Cancer: Rational Design, Optimization, and Senescence-Inducing Mechanisms

Experiments in miceEsophageal cancer

International Journal of Biological SciencesSep 17

Senescent Tumoral HLA-E Reshapes Microenvironment through Impairing NK Cell-Dendritic Cell-T Cell Network in Malignant Pleural Effusion from Lung Cancer

Cross-sectional study in peopleCellular senescence

Journal of Leukocyte BiologySep 2

Senescent cancer cells in immune surveillance and evasion: mechanisms and therapeutic implications

ReviewImmune response

Journal of Medicinal ChemistryJul 31

Peptide Inhibitors Targeting FOXO4-p53 Interactions and Inducing Senescent Cancer Cell-specific Apoptosis

Experiments in human cellsCancer

BiomaterialsJun 11

Targeting the senescent surfaceome through DPP4 antibody-functionalized nanoparticles. An application to cancer therapy

Experiments in miceInterventions

Aging and DiseaseMay 27

Anillin Recedes in p53-Dependent Senescence of Tumor Cells and Reappears in Cells Escaping from Senescence

Experiments in human cellsCellular senescence