Senescence-related markers
2 papers2 findings
- Cells2
Interventions
1Metformin
downin human cells1
1 study
Metformin
downin human cells1
Metformin decreases senescence-related markers in human cells.
“Experimental results show that ELIT exposure increased mitochondrial activity, oxidative stress, and senescence markers, particularly in T47D cells, effects that metformin mitigated.”
Cellsin ELIT-treated luminal breast cancer cells
Biochemical pharmacology25 Mar 2026
Associations
1ESR2
upin humans1
1 study
ESR2
upin humans1
ESR2 is associated with senescence-related markers in humans.
“Analysis of patient datasets revealed a positive correlation between ERβ gene (ESR2) expression and senescence-related markers in obese luminal breast cancer patients”
Humansin obese luminal breast cancer patients
Biochemical pharmacology25 Mar 2026
Latest
3 in 12 monthsJournal of Ginseng Research
Total saponins from Panax ginseng delay aging and cellular senescence via PI3K-AKT pathway in a rapid dual-system screening model of aging
Experiments in human cellsInterventions
Biochemical Pharmacology
Metformin reduces senescence induced by obesity-related inflammation in luminal breast cancer through estrogen receptor beta modulation
Experiments in human cellsMetformin
Acta Pharmacologica Sinica
UBC9-mediated p53 SUMOylation drives tubular senescence and exacerbates acute kidney injury in mice
Experiments in miceCellular senescence
Ecotoxicology and Environmental Safety
PARP1 promoter hypermethylation promotes arsenic-induced skin damage by driving telomere dysfunction-mediated keratinocyte senescence
Cohort study in peopleTelomerase and telomere maintenance
Journal of Diabetes
Taurine Alleviates Pancreatic β-Cell Senescence by Inhibition of p53 Pathway
Experiments in mouse cellsInterventions