Senescence-associated signatures

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Animals1

Interventions

1

Targeted genetic clearance of P21-POSITIVE cells

downin animals1

1 study

Targeted genetic clearance of P21-POSITIVE cells decrease senescence-associated signatures.
“Targeted genetic clearance of p21+ cells suppressed senescence-associated signatures within the fracture callus and accelerated fracture healing.”
Animalsfollowing fracturefracture callus
Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair
The Journal of clinical investigation16 May 2024

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