Papers on SA-β-gal positivity

117 papers6 new in 30 days

Tuesday, December 16

International Journal of Immunopathology and PharmacologyDec 16

Targeted chelation therapy decreases NLRP3 expression by vascular cells and acts as senomorphic in chronic kidney disorder induced vascular calcification

Experiments in animalsVascular calcification

Paper

Wednesday, November 26

Aging and DiseaseNov 26

Long-term Senolytic Treatment Prevents Endothelial Dysfunction in Arterial Aging

Experiments in miceSenolytics

Paper

Friday, November 14

Zhongguo Shi Yan Xue Ye Xue Za ZhiNov 14

Hydroxysafflor Yellow A Ameliorates the Replicative Senescence of Human Umbilical Cord Mesenchymal Stem Cells by Suppressing Oxidative Stress

Experiments in human cellsInterventions

Paper

Thursday, October 30

FASEB JournalOct 30

Mechanical Stretch Prevents Senescence-Associated Osteogenic Impairment in Mesenchymal Stem Cells via CXCR4/PI3K/AKT Signaling

Experiments in cellsInterventions

Paper

Thursday, July 3

Frontiers in Cardiovascular MedicineJul 3

N6-methyladenosine RNA landscape in the aged mouse hearts

Experiments in miceMechanisms

Paper

Saturday, June 7

International ImmunopharmacologyJun 7

Treatment with senolytic drugs ameliorates steroid-induced osteonecrosis of the femoral head by inhibiting osteoclastogenesis

Experiments in miceSenolytics

Paper

Thursday, May 15

Tissue & CellMay 15

BDNF alleviates senescence and enhances osteogenic differentiation in bone marrow mesenchymal stem cells via the TrkB/PI3K/AKT pathway

Experiments in human cellsInterventions

Paper

Wednesday, April 30

American Journal of Physiology Lung Cellular and Molecular PhysiologyApr 30

Lower levels of senescence in human lung mesenchymal stromal cells compared with lung fibroblasts: implications for tissue regeneration in COPD

Experiments in human cellsCellular senescence

Paper

Friday, April 25

Annals of MedicineApr 25

Accelerated senescence of bone marrow erythrocyte precursors in myelodysplastic syndrome

Cross-sectional study in peopleCellular senescence

Paper

Thursday, April 24

IBRO Neuroscience ReportsApr 24

Natural polyphenol mangiferin delays neuronal cell senescence by inhibiting neuroinflammation mediated by microglial activation

Experiments in miceInterventions

Paper

Wednesday, April 16

BMC Oral HealthApr 16

High glucose induces senescence in synovial mesenchymal stem cells through mitochondrial dysfunction

Experiments in cellsCellular senescence

Paper

Thursday, March 27

International Journal of Molecular SciencesMar 27

Network Pharmacology Combined with Experimental Validation to Investigate the Effects and Mechanisms of Aucubin on Aging-Related Muscle Atrophy

Experiments in wormsMuscle atrophy

Paper

Thursday, March 13

International ImmunopharmacologyMar 13

Aging and autophagic phenotypic changes in bone marrow mesenchymal stem cells in glucocorticoid-induced osteonecrosis

Experiments in miceAutophagy

Paper

Monday, February 24

Experimental Cell ResearchFeb 24

Human umbilical cord mesenchymal stem cell-derived exosome ameliorate doxorubicin-induced senescence

Experiments in miceInterventions

Paper

Wednesday, February 5

PreprintFeb 5

Metformin Prevents Oxidative Stress-Induced Premature Senescence in Astrocyte Cells

Preprint: experiments in cellsMetformin

Paper

Friday, January 24

Journal of Environmental ManagementJan 24

Long-chain chlorinated paraffins (LCCPs) exposure causes senescence and inflammatory damage in cardiomyocytes

Experiments in cellsCellular senescence

Paper

Monday, January 6

Environmental Health and Preventive MedicineJan 6

Arsenite exposure induces premature senescence and senescence-associated secretory phenotype (SASP) in human hepatocyte-derived cell line Huh-7

Experiments in human cellsSenescence-associated secretory phenotype (SASP)

Paper

Thursday, October 24

Xi Bao Yu Fen Zi Mian Yi Xue Za ZhiOct 24

Iron overload impairs mitochondrial function, induces neutrophil aging, inhibits its bactericidal ability, and exacerbates mouse peritonitis

Experiments in miceOxidative phosphorylation

Paper

Tuesday, October 22

Journal of Applied BiomedicineOct 22

Astragaloside IV confronts amyloid-beta-induced astrocyte senescence via hsp90aa1

Experiments in human cellsInterventions

Paper

Thursday, August 22

Stem CellsAug 22

Integrin-linked kinase control dental pulp stem cell senescence via the mTOR signaling pathway

Experiments in ratsJAK–STAT signaling

Paper

Thursday, May 2

Tissue Engineering Part AMay 2

Effect of Chitosan on Synovial Membrane Derived Cells and Anterior Cruciate Ligament Fibroblasts

Experiments in human cellsInterventions

Paper

Wednesday, April 17

InflammationApr 17

ROS-Induced Gingival Fibroblast Senescence: Implications in Exacerbating Inflammatory Responses in Periodontal Disease

Experiments in human cellsDNA damage response

Paper

Tuesday, March 19

Pediatric ResearchMar 19

Overexpression of miR-22-3p and miR-29c-3p in CFU-Hill colonies is related to senescence process among children with low birth weight

Cross-sectional study of 61 peopleCellular senescence

Paper

Sunday, March 10

Cell Death DiscoveryMar 10

Uric acid-driven NLRP3 inflammasome activation triggers lens epithelial cell senescence and cataract formation

Study in peopleNLRP3 inflammasome

Paper

Tuesday, February 6

InflammationFeb 6

FSTL1 Accelerates Nucleus Pulposus Cell Senescence and Intervertebral Disc Degeneration Through TLR4/NF-κB Pathway

Study in peopleCellular senescence

Paper

Monday, January 22

BiologyJan 22

Red Ginseng Attenuates the Hepatic Cellular Senescence in Aged Mice

Experiments in miceInterventions

Paper

Wednesday, December 20

Journal of Neuro-oncologyDec 20

Oncogene-induced senescence in meningiomas-an immunohistochemical study

Cohort study of 318 peopleCellular senescence

Paper

Monday, November 6

Journal of Pathology and Translational MedicineNov 6

Senescent tumor cells in colorectal cancer are characterized by elevated enzymatic activity of complexes 1 and 2 in oxidative phosphorylation

Cross-sectional study in peopleOxidative phosphorylation

Paper

Saturday, June 10

International Journal of Molecular SciencesJun 10

ZIM1 Combined with Hydrogel Inhibits Senescence of Primary PαS Cells during In Vitro Expansion

Experiments in mouse cellsInterventions

Paper

Friday, June 2

Cell TransplantationJun 2

Dexamethasone Induces Senescence-Associated Changes in Trabecular Meshwork Cells by Increasing ROS Levels Via the TGFβ/Smad3-NOX4 Axis

Experiments in miceCellular senescence

Paper