RUNX2-positive osteoprogenitor numbers

1. CD36 decreases RUNX2-positive osteoprogenitor numbers in mice.

   “Adeno-associated virus-mediated CD36 knockdown in ovariectomized mice restored trabecular bone parameters and increased RUNX2-positive osteoprogenitor numbers compared to controls.”

   Animalsshown by knockdown in ovariectomized micebone marrowfemales

   Single-cell transcriptomics identifies CD36 as a negative regulator of osteogenic differentiation in murine osteoporosis

   Joint bone spine·7 Jul 2026

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