Pyramidal cells

1 paper1 finding

Animals1

Upstream

1

SLC9A6

downin rats1

1 study

SLC9A6 decreases pyramidal cells in rats.
“In the hippocampus and cortex, lysosome defects precede loss of pyramidal cells.”
AnimalsNHE6-nullhippocampus and cortexmales
Early lysosome defects precede neurodegeneration with amyloid-β and tau aggregation in NHE6-null rat brain
Brain : a journal of neurology14 Sep 2022

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The Journal of Comparative NeurologyYesterday

Age-Related Changes in Density, Arborization, and NMDA Receptor Expression in Somatostatin Interneurons of the Mouse mPFC

Experiments in miceMechanisms

bioRxiv28 Sep

APOE4 alters olfactory neurons across age and sex in mice

Whole-cell recordings in adult and aged humanized mice showed that APOE4 modified pyramidal cell and interneuron properties depending on both age and sex.Whole-cell recordings in adult and aged humanized mice showed that APOE4 modified pyramidal cell and interneuron properties depending on both age and sex.

Preprint: experiments in animalsAPOE

Mechanisms of Ageing and Development15 Sep

Age-related electrophysiological changes in layer 5 pyramidal cells and interneurons of the rat medial prefrontal cortex

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Loss of calbindin and rise in pT217-tau in aging monkey prefrontal cortical dendrites

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Synapse9 Apr

Effect of Healthy Aging on the Cytoarchitecture of Layer V Pyramidal Neurons in the Motor Cortex of Rats: A Golgi Study

Experiments in animalsMechanisms

PLOS Biology30 Jan

Five energy metabolism pathways show distinct regional distributions and lifespan trajectories in the human brain

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The Journals of Gerontology, Series A6 Dec

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Exploring the Effects of Changes in Dietary Protein Content on Naturally Aging Mice Based on Comprehensive Quantitative Scoring and Metabolomic Analysis

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Phylogenetic divergence of GABAB receptor signaling in neocortical networks over adult life

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Anesthesiology28 Mar

Hippocampal Neural Dynamics and Postoperative Delirium-like Behavior in Aged Mice

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