AgingResearch.NewsJoin free

SLC9A6

Gene

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Foundation for Angelman Syndrome Therapeutics and 5 more
  • Animals1

Effects

2

Pyramidal cells

downin rats1

1 study

  1. SLC9A6 decreases pyramidal cells in rats.

    “In the hippocampus and cortex, lysosome defects precede loss of pyramidal cells.”

    AnimalsNHE6-nullhippocampus and cortexmales

    Early lysosome defects precede neurodegeneration with amyloid-β and tau aggregation in NHE6-null rat brain

    Brain : a journal of neurology14 Sep 2022

More on Pyramidal cells

Purkinje cells

downin rats1

1 study

  1. SLC9A6 decreases Purkinje cells in rats.

    “NHE6-null rats demonstrated an early and rapid loss of Purkinje cells in the cerebellum”

    AnimalsNHE6-nullcerebellummales

    Early lysosome defects precede neurodegeneration with amyloid-β and tau aggregation in NHE6-null rat brain

    Brain : a journal of neurology14 Sep 2022

More on Purkinje cells

Latest

Related