PP2A activity

2 papers1 finding

Animals2

Upstream

1

SAMP8 phenotype

downin mice1

1 study

SAMP8 phenotype decreases PP2A activity in mice.
“Significant reduction of PP2A activity was observed in the liver nucleus of SAMP8.”
Animalsliver nucleus
Age-related changes of forkhead transcription factor FOXO1 in the liver of senescence-accelerated mouse SAMP8
Archives of gerontology and geriatrics24 Jun 2013

Latest

2 in 12 months

Cellular Oncology8 Jun

Protein phosphatase 2 phosphatase activator (PTPA) promotes oncogene-induced senescence and carboplatin response in human malignant pleural mesothelioma cells

Experiments in human cellsCellular senescence

Aging Cell17 Mar

The Adiponectin-PP2A Pathway Confers Cognitive Benefits of Physical Exercise Against Chronic Stress-Induced Tau Hyperphosphorylation in the Hippocampus

Experiments in miceExercise

Environmental Pollution4 Aug

Microcystin-LR facilitates pubertal bone retardation by interfering with glutamine metabolism to accelerate stem cell senescence through Hippo/GLS pathway

Experiments in miceAmino acid metabolism

Cell Reports27 May

Sch9S6K controls DNA repair and DNA damage response efficiency in aging cells

Experiments in yeastDNA repair

Toxins27 Mar

Mutations at Two Key Sites in PP2A Safeguard Caenorhabditis elegans Neurons from Microcystin-LR Toxicity

Experiments in wormsMechanisms

Archives of Gerontology and Geriatrics24 Jun

Age-related changes of forkhead transcription factor FOXO1 in the liver of senescence-accelerated mouse SAMP8

Experiments in miceFOXO1