Poly ADP-ribosylation

2 papers study it13 more mention it

Animals2

Latest

1 paper in 12 months

Yakugaku ZasshiApr 30

Function, Regeneration, and Proliferation of Pancreatic β-Cells Centered on NAD

ReviewMechanisms

Biochemical and Biophysical Research CommunicationsJun 16

Loss of DNA replication fork protection by TIMELESS degradation supports oncogene-induced senescence

Experiments in human cellsCellular senescence

Cell Death & DiseaseOct 2

Inhibition of poly(ADP-Ribosyl)ation reduced vascular smooth muscle cells loss and improves aortic disease in a mouse model of human accelerated aging syndrome

Experiments in miceInterventions

Aging CellFeb 28

Loss of smelling is an early marker of aging and is associated with inflammation and DNA damage in C57BL/6J mice

Experiments in miceInterventions

Molecular MetabolismAug 21

Pgc-1α controls epidermal stem cell fate and skin repair by sustaining NAD⁺ homeostasis during aging

Experiments in miceSkin

OncotargetApr 20

Decreased expression of the translation factor eIF3e induces senescence in breast cancer cells via suppression of PARP1 and activation of mTORC1

Experiments in cellsMechanisms

The Journal of Biological ChemistryOct 13

Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity

Experiments in cellsInterventions

International Journal of Molecular SciencesSep 13

A Multi-Endpoint Approach to Base Excision Repair Incision Activity Augmented by PARylation and DNA Damage Levels in Mice: Impact of Sex and Age

Experiments in animalsMechanisms

AgingMay 16

Poly(ADP-ribosyl)ation and DNA repair synthesis in the extracts of naked mole rat, mouse, and human cells

Experiments in cellsMechanisms

Progress in Molecular Biology and Translational ScienceFeb 8

Regulatory Effects of NAD⁺ Metabolic Pathways on Sirtuin Activity

ReviewMechanisms