Physiologic reserve

Biomarker

1 paper studies it327 more mention it2 findings

  • Humans1

Associations

1

Superaging

upin humans1

1 study
  1. Physiologic reserve predicts superaging in humans.

    “higher physiologic reserve predicted linear increases in odds of SA”

    HumansHIVn = 396

    Cognitive and Physiologic Reserve Independently Relate to Superior Neurocognitive Abilities in Adults Aging With HIV

    Journal of acquired immune deficiency syndromes (1999)

  2. Superaging is associated with physiologic reserve in humans (ds >= 0.38, ps < 0.05).

    “SA exhibited significantly higher cognitive and physiologic reserve compared with CN and cognitively impaired ( d s ≥ 0.38, p s < 0.05).”

    HumansHIVn = 396

    Cognitive and Physiologic Reserve Independently Relate to Superior Neurocognitive Abilities in Adults Aging With HIV

    Journal of acquired immune deficiency syndromes (1999)

Funding

1 grant since 2019

National Institute on AgingUS$65.1k

Latest

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Research Square

Higher physical reserve linked to lower heart risk after breast cancer

Among breast cancer survivors, 10-year heart failure risk ranged from 0.80% to 3.61% across categories of a score combining lung function, grip strength and waist size.Among breast cancer survivors, 10-year heart failure risk ranged from 0.80% to 3.61% across categories of a score combining lung function, grip strength and waist size.

Preprint: cohort · 5,605 peopleBreast cancer
Journal of Global Health

Higher frailty over time linked to osteoporosis risk

Compared with low-frailty groups, higher-frailty groups generally faced greater osteoporosis risk in three observational cohorts of adults aged 50 and older.Compared with low-frailty groups, higher-frailty groups generally faced greater osteoporosis risk in three observational cohorts of adults aged 50 and older.

Cohort · 57,940 peopleOsteoporosis
Research Square

Illness burden linked to survival in older Thai adults

Estimated five-year survival was 85.9% with scores of 3 to 4 for coexisting illnesses, versus 50.1% with scores of 7 or higher.Estimated five-year survival was 85.9% with scores of 3 to 4 for coexisting illnesses, versus 50.1% with scores of 7 or higher.

Preprint: cohort · 709 peoplePopulations
ERJ Open Research

Lung function decline and scan findings linked to later frailty

Each 1%-per-year drop in the volume of air forcibly exhaled in one second was linked to 1.47 times the odds of frailty at 10 years.Each 1%-per-year drop in the volume of air forcibly exhaled in one second was linked to 1.47 times the odds of frailty at 10 years.

Cohort · 2,354 peopleLung