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Peroxisome number

Biomarker

2 papers study it2 more mention it3 findings

  • Model organisms1
  • Cells1

Interventions

1

Mono-unsaturated fatty acids

upin worms1

1 study

  1. Mono-unsaturated fatty acids increase peroxisome number in worms.

    “MUFAs upregulate not only lipid droplet number but also peroxisome number”

    Model organisms

    Lipid droplets and peroxisomes are co-regulated to drive lifespan extension in response to mono-unsaturated fatty acids

    Nature cell biology

More on Mono-unsaturated fatty acids

Associations

2

Mitochondrial dysfunction and fragmentation

upin yeast cells1

1 study

  1. Peroxisome number is associated with mitochondrial dysfunction and fragmentation in yeast cells.

    “replicatively aged cells with increased peroxisome number also display mitochondrial dysfunction and fragmentation in all the strains studied.”

    Cellsall studied strains

    Increased peroxisome proliferation is associated with early yeast replicative ageing

    Current genetics

Replicative age

upin yeast cells1

1 study

  1. Replicative age is associated with peroxisome number in yeast cells.

    “Increase in the number of peroxisomes in replicatively aged mother cells of wild-type yeast was observed when cultured in both peroxisome-inducing and non-inducing medium.”

    Cellswild-type cells in peroxisome-inducing and non-inducing mediummother cell

    Increased peroxisome proliferation is associated with early yeast replicative ageing

    Current genetics

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