PEX11

PEX11 shortens lifespan in yeast cells.

“Reduced chronological lifespan of all the mutants was observed in peroxisome-inducing growth conditions.”

Cellsin peroxisome-inducing growth conditions

The nexus between peroxisome abundance and chronological ageing in Saccharomyces cerevisiae

Biogerontology·Oct 9, 2022

PEX11 increases peroxisome proliferation in yeast cells.

“when cultured in oleic acid, young mother cells devoid of Pex11 showed reduced peroxisome proliferation compared to old mother cells.”

Cellsshown by absence of Pex11; cultured in oleic acid; compared with old mother cellsmother cell

Increased peroxisome proliferation is associated with early yeast replicative ageing

Current genetics·Feb 27, 2022