p16Ink4a mRNA
5 papers1 finding
- Human trial2
- Humans1
- Animals1
- Cells1
Interventions
1High-intensity interval training
downin humans1
1 study
High-intensity interval training
downin humans1
High-intensity interval training decreases p16Ink4a mRNA in humans (-82%, p < 0.01).
“The maximum decrease in p16INK4a mRNA levels within muscle tissues occurred at 3 h post-exercise (-82%, p < 0.01)”
Human trialskeletal muscle3 hmalesn = 12
Senolytic effects of exercise in human muscles require acute inflammation
AgingMay 15, 2024
Latest
2 in 12 monthsGSA 2025 Abstract
T Cell Activation Triggers Calcium-Dependent Expression of the Aging Marker p16INK4a
Experiments in human cellsCDKN2A
Journal of the International Society of Sports Nutrition
Amino acid supplementation accelerates resolution of exercise-induced phagocyte infiltration in human skeletal muscle
Randomized trial in 10 peopleResistance training
Aging
Senolytic effects of exercise in human muscles require acute inflammation
Randomized trial in 12 peopleMuscle
Cell Cycle
Sustained activation of NF-κB through constitutively active IKKβ leads to senescence bypass in murine dermal fibroblasts
Experiments in mouse cellsCellular senescence
Research Square
Ibuprofen delays senolytic effects of exercise in human skeletal muscle: A randomized control crossover trial
Preprint: trial in peopleInterventions
Frontiers in Oncology
Associations between exercise capacity, p16INK4a expression and inflammation among adult survivors of childhood cancer
Study in peopleBiomarkers
Aging
Licochalcone A activation of glycolysis pathway has an anti-aging effect on human adipose stem cells
Experiments in human cellsInterventions