Experimental & Molecular Medicine
Macrophage pyroptosis drives luminal senescence and club-cell reprogramming in 5α-reductase inhibitor-treated prostatic hyperplasia

Study in peopleMechanisms
Mice, declared no competing interests
- 5alpha-reductase inhibitors
- Pyroptosis
- GSDMD
- Benign prostatic hyperplasia
- Cleaved-GSDMD+ macrophages
- Mice
The paper
Peking University
Experimental & Molecular Medicine, 7 Oct 2026