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P16 mRNA expression

There are 6 papers on P16 mRNA expression in aging research: 1 trial and 1 observational study in people, 1 in animals, 2 in cells.

Biomarker

6 papers study it2 findings

See all 6 papers on P16 mRNA expression

  • Human trial1
  • Humans1
  • Animals1
  • Cells2

Interventions

2

Chia seed

downin mice1

1 study

  1. Chia seed decreases P16 mRNA expression in high-fat diet-fed SAMP8 mice; partial reduction.

    “chia seed partially reduced p16 and CD68 mRNA expression”

    Animalsin high-fat diet-fed SAMP8 mice; partial reductionepididymal adipose tissue10%

    Chia Seed Supplementation Reduces Senescence Markers in Epididymal Adipose Tissue of High-Fat Diet-Fed SAMP8 Mice

    Journal of medicinal food

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Fish oil

upin humans1

1 study

  1. Fish oil increases P16 mRNA expression in humans (type 2 diabetes) (between-group p = 0.028).

    “Short-time DHA-enriched fish oil supplementation caused increased levels of P16 expression and a decline in telomerase activity compared with the control group”

    Human trialtype 2 diabetesDHA-enrichedperipheral blood mononuclear cell2.4 gr8 weeksn = 72

    DHA-enriched fish oil upregulates cyclin-dependent kinase inhibitor 2A (P16INK) expression and downregulates telomerase activity without modulating effects of PPARγ Pro12Ala polymorphism in type 2 diabetic patients: A randomized, double-blind, placebo-controlled clinical trial

    Clinical nutrition (Edinburgh, Scotland)

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