Organ biological age

Biomarker

2 papers1 finding

  • Humans1

Associations

1

Cardiovascular disease

upin humans1

1 study
  1. Organ biological age predicts cardiovascular disease in humans.

    “biological ages of cardiovascular system, bone, metabolism, brain and the whole body show stronger associations with cardiovascular events risk than chronological age.”

    Humansn = 904

    Synergistic and heterogeneous aging using composite phenotypes and multiple organ systems aging clocks

    Communications medicine1 Dec 2025

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Aging Cell

Higher birthweight and breastfeeding linked to slower organ aging

In UK Biobank participants, higher birthweight was associated with slower aging in 11 organs, while breastfeeding was linked to slower intestine and adrenal aging.In UK Biobank participants, higher birthweight was associated with slower aging in 11 organs, while breastfeeding was linked to slower intestine and adrenal aging.

Cohort study of 29,713 peoplePopulations
Research Square

Organ age acceleration and mortality risk reflect distinct biological processes

Multi-omics clocks across fourteen organs reveal divergent molecular programs and uncover thirteen candidate genes separating age acceleration from mortality.Multi-omics clocks across fourteen organs reveal divergent molecular programs and uncover thirteen candidate genes separating age acceleration from mortality.

Preprint: cohort study of 409,206 peopleBiomarkers
bioRxiv

Blood and facial photos track organ aging and senescence scores in humans

Researchers used transcriptomic models, DNA methylation, and images across multiple human cohorts to infer tissue-specific biological age and hallmark burdens.Researchers used transcriptomic models, DNA methylation, and images across multiple human cohorts to infer tissue-specific biological age and hallmark burdens.

Preprint: cohort study in peopleBiomarkers