Oligodendrocytes

Biomarker

1 paper1 finding

  • Humans1

Associations

1

Superaging

downin humans1

1 study
  1. Superaging is associated with oligodendrocytes in humans (p <.001).

    “Oligodentrocytic reactivity was significantly lower in SuperAgers than controls ( p <.001).”

    Humansin individuals with postmortem PARThippocampusn = 8

    Immune Reactivity in Hippocampal Subregions of Cognitive SuperAgers with Primary Age‐related Tauopathy

    AAIC 2025 abstract23 Dec 2025

Funding

2 grants since 2022

National Institute on AgingUS$2.9m

Latest

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medRxiv

Spinal cord charts map age patterns and disease differences

Different upper spinal cord measurements peaked at ages 29.7–44.1 years in reference charts based on scans of 10,159 healthy people aged 8–85.Different upper spinal cord measurements peaked at ages 29.7–44.1 years in reference charts based on scans of 10,159 healthy people aged 8–85.

Preprint: cross-sectional study of 10,159 peopleBiomarkers
bioRxiv

Cell counts may miss dementia-linked changes in human brains

An observational analysis of human brain tissue compared gene activity and cell proportions across normal cognition, disease-related aging and dementia.An observational analysis of human brain tissue compared gene activity and cell proportions across normal cognition, disease-related aging and dementia.

Preprint: study in peopleMechanisms