ESC Congress 2026 Abstract
Circular RNA helps protect against heart aging in mice
Deleting circHIPK3 impaired heart function in mice; increasing it restored a heart-protective protein and suppressed an aging-associated pathway.Deleting circHIPK3 impaired heart function in mice; increasing it restored a heart-protective protein and suppressed an aging-associated pathway.
Mouse studyMechanisms
Who was studiedCircHIPK3 knockout mice
What changedMice genetically engineered to lack circHIPK3 in heart muscle cells developed impaired heart function, scarring and aging-related changes
The catchThis conference abstract gave no sample sizes