Mutation frequency

1 paper

Humans1

Latest

5 in 12 months

Aging Cell21 Aug

Aged Mitochondrial DNA Is Associated With Aberrant Acute Exercise-Induced Redox Responses in Human Skeletal Muscle

Cohort study of 22 peopleImmune response

medRxiv11 Aug

Classical driver mutations are not associated with metachronous lesion risk in patients undergoing post-polypectomy surveillance following removal of conventional adenomas in a bowel screening setting

Preprint: cohort study of 723 peopleBiomarkers

GeroScience26 Mar

Quadriceps mitochondrial DNA quantity, quality, and gene expression after 2 years of calorie restriction: exploratory results from the CALERIE trial

Randomised trial in 93 peopleDietary restriction

Nature Communications15 Feb

Blood-based epigenetic instability linked to human aging and disease

Cohort study of 8,886 peopleBiomarkers

International Journal of Biological Sciences9 Dec

H3K27 Acetylation-driven IGF2BP2 Mutates during the Aging of MSCs, thereby Influencing Osteogenic Differentiation and Bone Aging

Experiments in miceBones and joints

Scientific Reports16 Oct

Aging alters genomic instability at endogenous mutation hotspots in mice

Experiments in miceDNA damage response

Aging Cell30 Sep

Aging Increases Short, Inverted Repeat-Mediated Genomic Instability In Vivo

Experiments in animalsMechanisms

Advances in Experimental Medicine and Biology29 Aug

Mitochondrial DNA Deletion Mutations: A Molecular Cause of Age-Induced Skeletal Muscle Fiber Dysfunction and Fiber Death Contributing to Sarcopenia

ReviewMechanisms