mtDNA mutation burden

1 paper

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3 in 12 months

Frontiers in Endocrinology13 Jul

The EV-mitochondrial outsourcing network as a therapeutic target for age-related testosterone deficiency: from network collapse to clinical intervention

ReviewMitochondrion

Journal of Neurology7 Jun

Distinct age-related pattern of mitochondrial somatic mutations across multiple sclerosis phenotypes

Cohort study of 404 peopleMitochondrion

iScience28 Feb

Accumulated mtDNA mutations are linked to specific impairments in NADH-linked respiration

Experiments in miceOxidative phosphorylation

Nature Communications16 Jan

NAD⁺ dependent UPRmt activation underlies intestinal aging caused by mitochondrial DNA mutations

Experiments in miceMitochondrion

Aging Cell6 Sep

Voluntary exercise normalizes the proteomic landscape in muscle and brain and improves the phenotype of progeroid mice

Experiments in miceExercise