Mitochondrial calcium overload
2 papers1 finding
- Animals1
- Model organisms1
Upstream
1vimar
upin flies1
1 study
vimar
upin flies1
vimar induces mitochondrial calcium overload in flies.
“Overexpression of Vimar in neurons resulted in premature aging and mitochondrial calcium overload.”
Model organismsoverexpression in neuronsbrain
Vimar/RAP1GDS1 promotes acceleration of brain aging after flies and mice reach middle age
Communications biologyApr 15, 2023
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Glucose restriction induces degeneration of neurons with mitochondrial DNA depletion by altering ER-mitochondria calcium transfer
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Mitochondrial calcium uniporter promotes kidney aging in mice through inducing mitochondrial calcium-mediated renal tubular cell senescence
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Vimar/RAP1GDS1 promotes acceleration of brain aging after flies and mice reach middle age
Experiments in fliesMechanisms