National Institute of Diabetes and Digestive and Kidney DiseasesUS$2.1mNational Cancer InstituteUS$179kNational Heart, Lung, and Blood InstituteUS$496.4k
In a mouse heart attack experiment, particles released by aged stem cells engineered to produce more apelin, a signalling protein, improved heart function.In a mouse heart attack experiment, particles released by aged stem cells engineered to produce more apelin, a signalling protein, improved heart function.
In a rat experiment, cell-released packages from young donors had stronger tissue-repair effects than those from older donors after blood supply was restricted.In a rat experiment, cell-released packages from young donors had stronger tissue-repair effects than those from older donors after blood supply was restricted.
Aged male mice showed far larger proteomic shifts than females following microglial removal, including alterations in synaptic and mitochondrial proteins.Aged male mice showed far larger proteomic shifts than females following microglial removal, including alterations in synaptic and mitochondrial proteins.
Researchers identified coordinated changes in DNA methylation, miRNAs, and gene expression distinguishing older female monkeys with slower gait from middle-aged…Researchers identified coordinated changes in DNA methylation, miRNAs, and gene expression distinguishing older female monkeys with slower gait from middle-aged counterparts.
Delivering miR-193b-3p improved muscle repair in injured mice and targeted a protein elevated in sarcopenic human tissue.Delivering miR-193b-3p improved muscle repair in injured mice and targeted a protein elevated in sarcopenic human tissue.