Midlife plasma proteins

Midlife plasma proteins are associated with late-life prefrailty and frailty in humans (12 proteins associated with prefrailty; 221 with frailty).

“12 and 221 proteins were associated with prefrailty and frailty in later life, respectively (FDR p < 0.05).”

HumansAdjusted for demographics, health behaviors, kidney function, total cholesterol, and comorbiditiesplasmaapproximately 20 years55.8% womensn = 4,189

Mid-life plasma proteins associated with late-life prefrailty and frailty: a proteomic analysis

GeroScience·10 Jun 2024