Metabolic dysfunction markers

There are 4 papers on metabolic dysfunction markers in aging research: 3 observational studies in people, 1 review.

Biomarker

4 papers study it1 more mentions it4 findings

See all 5 papers on metabolic dysfunction markers

“within 2,847 subjects meeting all conventional "normal" criteria (BMI <25, HbA1c <5.7%), structural parameters identified a high-risk subgroup with 10.9-fold elevated metabolic dysfunction markers”
Structural biophysical parameters for pre-disease metabolic dysfunction detectionZenodo (CERN European Organization for Nuclear Research)2026doi:10.5281/zenodo.18141544
  • Humans3

Interventions

1

Taurine

downin humans1

1 study
  1. Taurine decreases metabolic dysfunction markers in humans.

    “taurine supplementation significantly improved markers of metabolic dysfunction (including hemoglobin A1c, fasting blood glucose, fasting insulin, HOMA-IR, total cholesterol, triglycerides, and low-density lipoprotein)”

    Human trialn = 1,030

    Taurine supplementation as a therapeutic strategy for cellular senescence and chronic inflammation in long COVID: a systematic review and meta-analysis

    BMC infectious diseases

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Associations

3

Perirenal fat thickness

mixedin humans1

1 study
  1. Perirenal fat thickness is associated with metabolic dysfunction markers in humans (obesity).

    “peri-renal fat showed significant positive association with fasting glycemia and inverse association with HDL.”

    Humansobesityperirenal adipose tissue

    Ultrasound evaluation of epicardial fat and Eco-Obesity body composition assessment

    Frontiers in endocrinology

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Epicardial adipose tissue thickness

mixedin humans1

1 study
  1. Epicardial adipose tissue thickness is associated with metabolic dysfunction markers in humans (obesity).

    “EAT PPR correlated positively with glycemia, HOMA-IR, triglycerides, and negatively with HDL cholesterol”

    Humansobesityposterior cardiac recess projectionepicardial adipose tissue

    Ultrasound evaluation of epicardial fat and Eco-Obesity body composition assessment

    Frontiers in endocrinology

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Structural biophysical parameters

upin humans1

1 study
  1. Structural biophysical parameters are associated with metabolic dysfunction markers in humans within 2,847 subjects meeting all conventional normal criteria (BMI <25, HbA1c <5.7%) (10.9-fold elevated, p<10−61).

    “within 2,847 subjects meeting all conventional "normal" criteria (BMI <25, HbA1c <5.7%), structural parameters identified a high-risk subgroup with 10.9-fold elevated metabolic dysfunction markers”

    Humanswithin 2,847 subjects meeting all conventional normal criteria (BMI <25, HbA1c <5.7%)n = 2,847

    Structural biophysical parameters for pre-disease metabolic dysfunction detection

    Zenodo (CERN European Organization for Nuclear Research)Preprint

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Dec 2025: 0Jan 2026: 2Feb 2026: 0Mar 2026: 1Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 03 papers in 12 months