Memory CD4 T cells

Biomarker

4 papers2 findings

  • Humans4

Upstream

1

Age

upin humans1

1 study
  1. Age increases memory CD4 T cells in humans.

    “Conversely, the percentage of memory CD4 T cells increased”

    Humansblood

    Peripheral lymphocyte phenotypic characteristics in healthy populations across the lifespan, from infancy to older adults

    Laboratory medicineMar 31, 2025

Associations

1

SARS-CoV-2 cellular immune response

downin humans1

1 study
  1. Memory CD4 T cells predict SARS-CoV-2 cellular immune response in humans.

    “In a multivariate model, only the proportions of memory CD4+ T cells and CD28null T cells independently predicted the cellular response.”

    Humansmultivariate model in hemodialysis patients after BNT162b2 vaccinationn = 189

    Immune Senescence Markers Predict the Cellular Immune Response to BNT162b2 Vaccination in Hemodialysis Patients

    Open forum infectious diseasesOct 31, 2022

More on SARS-CoV-2 cellular immune response

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Nature Communications

Aged human T cells briefly regain young-like patrol behavior

In laboratory experiments, thicker fluid temporarily restored young-like monitoring behavior, particularly in a subgroup of aged human memory T cells.In laboratory experiments, thicker fluid temporarily restored young-like monitoring behavior, particularly in a subgroup of aged human memory T cells.

Human cell studyBlood and immune system