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M1/M2 macrophage ratio

Biomarker

4 papers study it1 more mentions it3 findings

  • Human trial1
  • Humans1
  • Animals2

Interventions

1

Aminolevulinic acid photodynamic therapy

upin humans1

1 study

  1. Aminolevulinic acid photodynamic therapy increases M1/M2 macrophage ratio in humans.

    “The ratio of M1/M2 and percentage of Langerhans cells also decreased with photoaging and increased after ALA-PDT.”

    Human trialphotoaged skinskin6 months

    Single cell transcriptome profiling reveals cutaneous immune microenvironment remodeling by photodynamic therapy in photoaged skin

    Frontiers in immunologyJun 19, 2023

More on Aminolevulinic acid photodynamic therapy

Effects

1

Type III collagen

no changein humans1

1 study

  1. M1/M2 macrophage ratio has no effect on type III collagen in humans.

    “however, there was no correlation with type III collagen”

    Humansfacial skin

    M1/M2 Macrophage Skewing is Related to Reduction in Types I, V, and VI Collagens with Aging in Sun-Exposed Human Skin

    JID innovations : skin science from molecules to population healthAug 12, 2023

More on Type III collagen

Associations

1

Type V and VI collagen

downin humans1

1 study

  1. M1/M2 macrophage ratio is associated with type V and VI collagen in humans.

    “the M1/M2 ratio was negatively correlated with the abundance of type V and VI collagen”

    Humansfacial skin

    M1/M2 Macrophage Skewing is Related to Reduction in Types I, V, and VI Collagens with Aging in Sun-Exposed Human Skin

    JID innovations : skin science from molecules to population healthAug 12, 2023

More on Type V and VI collagen

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