Experimental Gerontology
The guppy (Poecilia reticulata) is a useful model for analyzing age-dependent changes in metabolism, motor function, and gene expression
Experiments in zebrafishMechanisms
Papers on loss of homeostasis
52 papers
Tuesday, January 18
Friday, December 10
Antioxidants
Exploring Early Detection of Frailty Syndrome in Older Adults: Evaluation of Oxi-Immune Markers, Clinical Parameters and Modifiable Risk Factors
Cross-sectional study in peopleBiomarkers
Friday, November 5
bioRxiv
Age-induced P-bodies become detrimental and shorten the lifespan of yeast
Preprint: experiments in yeastMechanisms
Sunday, August 1
Wednesday, May 19
Sunday, March 14
bioRxiv
Engaging the complexity of diet and healthy aging in humans
Preprint: cohort study of 1,560 peoplePopulations
Tuesday, February 9
Cytokine & Growth Factor Reviews
Hallmarks of aging and immunosenescence: Connecting the dots
ReviewMechanisms
Thursday, January 28
Nature Reviews Molecular Cell Biology
Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing
ReviewMechanisms
Tuesday, September 8
Nature Communications
The precursor of PI(3,4,5)P₃ alleviates aging by activating daf-18(Pten) and independent of daf-16
Experiments in wormsInterventions
Sunday, August 30
Thursday, June 25
Biotechnology and Bioengineering
Aggregation-induced integrated stress response rejuvenates culture-expanded human mesenchymal stem cells
Experiments in cellsInterventions
Thursday, August 15
Brazilian Journal of Medical and Biological Research
Effects of natural aging and gender on pro-inflammatory markers
Cross-sectional study of 110 peopleInflammation
Wednesday, February 13
Aging Cell
Conservation of physiological dysregulation signatures of aging across primates
Experiments in non-human primatesBiomarkers
Saturday, December 1
Frontiers in Nutrition
Mesenchymal Stem Cell Therapy for Aging Frailty
Randomized trial in peopleMesenchymal stem cells
Tuesday, September 4
Free Radical Biology & Medicine
Reactive oxygen species, aging and articular cartilage homeostasis
ReviewCellular homeostasis
Tuesday, January 9
Frontiers in Physiology
Age-Related Changes in the Expression of the Circadian Clock Protein PERIOD in Drosophila Glial Cells
Experiments in fliesCircadian clock
Sunday, August 13
Journal of the American Medical Directors Association
Frailty Status in Older Adults Is Related to Alterations in Indoleamine 2,3-Dioxygenase 1 and Guanosine Triphosphate Cyclohydrolase I Enzymatic Pathways
Cross-sectional study in peopleBiomarkers
Friday, February 24
Cell Death & Disease
Inactivation of Lsd1 triggers senescence in trophoblast stem cells by induction of Sirt4
Experiments in mouse cellsCellular senescence
Saturday, January 28
Frontiers in Immunology
Calorie Restriction Attenuates Terminal Differentiation of Immune Cells
Experiments in miceDietary restriction
Tuesday, December 6
Journal of Cellular Biochemistry
Combined Therapy With Swimming Exercise and a Diet Supplemented With Diphenyl Diselenide Is Effective Against Age-Related Changes in the Hepatic Metabolism of Rats
Experiments in ratsInterventions
Saturday, July 30
Saturday, March 26
Maturitas
Prevalence and incidence of frailty in Aboriginal Australians, and associations with mortality and disability
Cohort study of 363 peopleDisability