Gut Microbes
Gut bacterial product changes blood fat levels in mice
Mice given a bile acid made by the gut bacterium Ruminococcus gnavus developed blood fat disturbances.Mice given a bile acid made by the gut bacterium Ruminococcus gnavus developed blood fat disturbances.
Mouse studyMechanisms
Who was studiedMice colonized with engineered bacteria
What changedMice colonized with isoCDCA-producing bacteria had higher total and LDL cholesterol than mice given vector-control bacteria
The catchNo R. gnavus knockout isolated whether its lipid effects require isoCDCA production