Journal of Hazardous Materials·Jan 14PFPeA exposure drives hepatoxicity and liver fibrosis via oxidative stress/Wnt5a-induced hepatocyte senescenceExperiments in miceCellular senescencePaper
Journal of Controlled Release·Dec 25Hepatocyte-specific partial cellular reprogramming via selective OSK mRNA lipid nanoparticle attenuates liver fibrosisExperiments in miceLiver fibrosisPaper
Current Atherosclerosis Reports·Dec 18Semaglutide and Tirzepatide for the Treatment of Obesity and Weight-Related Comorbidities: A Narrative ReviewReviewTirzepatidePaper
Gastroenterology·Dec 10Clusterin Drives Fiber Endocytosis by Mesothelial Cells to Resolve Liver FibrosisExperiments in miceLiver fibrosisPaper
Diabetes, Obesity & Metabolism·Dec 9Meta-analysis of clinically available pharmacotherapy of biopsy confirmed metabolic dysfunction associated steatohepatitis (MASH)Meta-analysis of randomized trialsMetabolic dysfunction-associated steatohepatitisPaper
Annals of Hepatology·Dec 6Genetic risk factors for MASLD/MASH and cardiovascular disease in elderly individualsCohort study of 5,244 peopleMechanismsPaper
Cell Biology and Toxicology·Nov 26NAD + in fatty liver disease: mechanistic insights and associated targetsReviewMechanismsPaper
GeroScience·Nov 24Necroptosis induced by MLKL overexpression in liver triggers cellular senescence and leads to chronic inflammation and fibrosisExperiments in miceCellular senescencePaper
Health Science Reports·Nov 20Liver Fibrosis and Risk of Incident Dementia in the General Population: Systematic Review With Meta-AnalysisReviewPopulationsPaper
Cureus·Nov 19Evaluation of the Short-Term Effect of Tirzepatide on Liver Fibrosis Biomarkers Stratified by the Fibrosis-3 Index (FIB-3) in Patients With Type 2 Diabetes MellitusStudy of 87 peopleTirzepatidePaper
JAMA Network Open·Nov 6Cost-Effectiveness of MASH Diagnosis and Management Approaches Among Those With Type 2 DiabetesComputational studyMetabolic dysfunction-associated steatohepatitisPaper
Geriatrics & Gerontology International·Nov 5The Role of an Elevated Fibrosis-4 Index in Neurocognitive Decline and Brain Volume Reduction in Older Adults With Metabolic Dysfunction-Associated Steatotic Liver DiseaseCross-sectional study of 384 peopleMetabolic dysfunction-associated steatotic liver diseasePaper
ENDO 2025 Abstract·Oct 23SUN-591 GLP1-RA, SGLT2i and Risk of Advanced Fibrosis in Patients with T2D:a Target Trial EmulationCohort study of 67,722 peopleSGLT2 inhibitorsPaper
ENDO 2025 Abstract·Oct 23SAT-536 How Do Metabolic Dysfunction Associated Steatosis Liver Disease (MASLD) and Depression in Veterans with T2DM respond to novel medicationsCross-sectional study of 58 peopleMetabolic dysfunction-associated steatotic liver diseasePaper
ENDO 2025 Abstract·Oct 23SAT-662 GLP-1 And Advanced NASH: Impact On Liver Fibrosis RegressionSystematic review of studies in peopleLiver fibrosisPaper
Clinical and Experimental Medicine·Oct 21Sarcopenic visceral obesity in patients with metabolic dysfunction-associated steatotic liver disease (MASLD)Cross-sectional study of 334 peopleVisceral obesityPaper
Przeglad Menopauzalny·Oct 20Burden of steatotic liver disease in postmenopausal women: NHANES 2017-2020 insightsCross-sectional study in peopleSteatotic liver diseasePaper
Colloids and Surfaces B, Biointerfaces·Oct 15Fe-Mn-IGF-AMD nanoparticles in accurate detection and treatment of liver cirrhosis via regulating relaxation coefficients and attenuating hepatocyte senescenceExperiments in animalsCirrhosisPaper
medRxiv·Oct 13Unveiling the Burden of MASLD and Liver Fibrosis in India: Novel Insights from the Phenome India Study into fibrosis without MASLDPreprint: cohort study of 7,764 peopleLiver fibrosisPaper
Phytomedicine·Oct 12Baicalein Induces Hepatic Stellate Cell Senescence and Attenuates Liver Fibrosis via CEBPZ/p53/HK2-Mediated Glycolysis InhibitionExperiments in miceLiver fibrosisPaper
Drug Design, Development and Therapy·Oct 6Deciphering the Role of Oroxylin A in Liver FibrosisReviewLiver fibrosisPaper
Phytomedicine·Oct 2Spermidine enhances macrophages anti-inflammatory and regenerative functions by improving mitochondrial fitnessExperiments in miceSpermidinePaper
bioRxiv·Oct 1Both terminal misfolding and polymerisation contribute to disease-relevant responses in cell models of α 1 -antitrypsin deficiency-associated liver diseasePreprint: experiments in cellsMechanismsPaper
Materials Today Bio·Sep 22aHSCs-targeted bimetallic nanozymes and luteolin-loaded liposomes: Synergistic reversal of liver fibrosis via antioxidant, cellular senescence, and cellular apoptotic mechanismsExperiments in animalsLiver fibrosisPaper
bioRxiv·Sep 21Modeling Fibrosis with MASH Patient Liver-Derived OrganoidsPreprint: experiments in human cellsMechanismsPaper
International Journal of Biological Macromolecules·Sep 15Roles and potential mechanisms of hepatic stellate cells activation mediated by epigenetics through insulin like growth factor 1 and receptor: A reviewReviewMechanismsPaper
Lipids in Health and Disease·Sep 9Body muscle mass versus fat mass: gender-specific associations with NAFLD and liver fibrosisCross-sectional study of 594 peopleLiver fibrosisPaper
Zhonghua Gan Zang Bing Za Zhi·Aug 28Study on the correlation between sarcopenia, energy metabolism, and the severity of liver disease in patients with type 2 diabetes mellitus combined with metabolic associated fatty liver diseaseCross-sectional study of 94 peopleMusclePaper
Theranostics·Aug 27Disturbance of cytoskeleton induced by ligustilide promotes hepatic stellate cell senescence and ameliorates liver fibrosisExperiments in miceLiver fibrosisPaper
Genome Medicine·Aug 16Aging increases susceptibility to liver fibrosis through enhanced NAT10-mediated ac4C modification of TGFβ1 mRNAExperiments in miceMechanismsPaper