Lipid droplet accumulation
Biomarker1 paper1 finding
- Animals1
Interventions
14-octyl itaconate
downin mice1Very low certainty
1 study
4-octyl itaconate
downin mice1Very low certainty
4-octyl itaconate decreases lipid droplet accumulation in mice.
Animalsparotid gland25 mg/kg4 weeksmales
4-Octyl itaconate restores parotid gland function in aging mice · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 30 Sep 2026
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4-Octyl itaconate restores parotid gland function in aging mice
The itaconate derivative reduces fibrosis and lipid buildup while curbing oxidative stress through AMPK signaling pathways.The itaconate derivative reduces fibrosis and lipid buildup while curbing oxidative stress through AMPK signaling pathways.