L1 mRNA
2 papers study it5 more mention it1 finding
- Humans1
- Animals1
Upstream
1Osteoarthritis
upin humans1
1 study
Osteoarthritis
upin humans1
Osteoarthritis increases L1 mRNA in humans.
“L1 mRNA was higher in CTL and SX compared to Y (p < 0.001 and p = 0.001, respectively).”
Humansend-stage osteoarthritis vs young healthy controlsskeletal muscle
BMC research notes
Latest
2 papers in 12 monthsNucleic Acids Research
Locus-specific LINE-1 mRNA expression reflects cell-type- and stimulus-specific senescence states
Computational studyCellular senescence
Aging Cell
Human cGAS Drives LINE-1 Transcriptional Activation to Trigger MAVS-Dependent Cellular Senescence
Experiments in human cellsCellular senescence
The Journal of Neuroscience
Sequence Diversity and Encoded Enzymatic Differences of Monocistronic L1 ORF2 mRNA Variants in the Aged Normal and Alzheimer's Disease Brain
Cross-sectional study of 31 peopleMechanisms
American Journal of Physiology Cell Physiology
Long-term voluntary wheel running effects on markers of long interspersed nuclear element-1 in skeletal muscle, liver, and brain tissue of female rats
Experiments in 34 ratsMuscle
BMC Research Notes
Effects of end-stage osteoarthritis on markers of skeletal muscle Long INterspersed Element-1 activity
Cross-sectional study in peopleTransposable element activity
American Journal of Physiology Cell Physiology
Five months of voluntary wheel running downregulates skeletal muscle LINE-1 gene expression in rats
Experiments in animalsInterventions