Kynurenic acid

2 papers

Animals1

Latest

6 in 12 months

Frontiers in Cellular Neuroscience2 Mar

Inflammatory mechanisms underlying early Alzheimer's disease pathology: evidence from the aging rhesus macaque brain

ReviewInflammation

Journal of Cachexia, Sarcopenia and Muscle2 Feb

Elevating Circulating L-Kynurenine Promotes Frailty in Aging Mice

Experiments in 262 miceTryptophan–kynurenine metabolism

International Immunopharmacology4 Jan

Tucidinostat ameliorates DSS-induced ulcerative colitis by inhibiting cellular senescence, modulating the p53 signaling pathway and cell cycle, and restoring the gut microbiota-metabolite Axis

Experiments in miceGut and microbiome

Molecular Psychiatry19 Dec

Kynurenic acid signaling expands in human and nonhuman primates and impairs dorsolateral prefrontal cortical cognition that is key to mental illness

Experiments in monkeysTryptophan–kynurenine metabolism

Cells26 Nov

Losing the Filter: How Kynurenine Pathway Dysregulation Impairs Habituation

ReviewTryptophan–kynurenine metabolism

Biochimie23 Nov

Effects of two longevity interventions, calorie restriction and rapamycin treatment, on the kynurenine-aryl hydrocarbon receptor pathway in aging skeletal muscle

Computational studyDietary restriction

GSA 2024 Abstract1 Jan

MULTIMODEL APPROACHES IDENTIFY CONSERVED ROLE OF TRP CATABOLIC PATHWAY IN THE REGULATION OF LIFE- AND HEALTHSPAN

Experiments in miceMechanisms