ISP index

Biomarker1 paper2 findings

Humans1

Associations

2

Cardiovascular mortality

upin humans1HR 2.88

1 study

ISP index raises the risk of cardiovascular mortality in humans (HR = 2.88, 95% CI: 1.36‒6.10).
Humansin MASLD, highest vs lowest ISP tertilemedian 8.25-year follow-upn = 3,187
A cardiometabolic risk phenotype index integrating insulin resistance, systemic inflammation, and psychological burden for mortality risk stratification in metabolic dysfunction-associated steatotic liver disease: an exploratory longitudinal analysis of a nationally representative cohort · Lipids in health and disease · 15 Sep 2026

Mortality

upin humans1HR 1.63

1 study

ISP index raises the risk of mortality in humans (HR = 1.63, 95% CI: 1.12-2.38).
Humansin MASLD, highest vs lowest ISP tertilemedian 8.25-year follow-upn = 3,187
A cardiometabolic risk phenotype index integrating insulin resistance, systemic inflammation, and psychological burden for mortality risk stratification in metabolic dysfunction-associated steatotic liver disease: an exploratory longitudinal analysis of a nationally representative cohort · Lipids in health and disease · 15 Sep 2026

Latest

1

Lipids in Health and DiseaseHumans26 Sep

A cardiometabolic risk phenotype index integrating insulin resistance, systemic inflammation, and psychological burden for mortality risk stratification in metabolic dysfunction-associated steatotic liver disease: an exploratory longitudinal analysis of a nationally representative cohort