Isocitrate

2 papers

Human trial1
Humans1

Latest

3 in 12 months

JMIR Research ProtocolsOct 16

Feasibility of High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumor and Young Adults With Isocitrate Dehydrogenase-Mutant Gliomas (HYPE): Protocol for a Randomized Controlled Trial

Study protocolExercise

bioRxivOct 2

Depletion of the isocitrate dehydrogenase 3 subunit IDHA-1 licenses germ cell-to-neuron direct reprogramming

Preprint: experiments in wormsEpigenetic regulation of gene expression

Journal of Sport and Health ScienceSep 17

Participation in an exercise program after primary glioblastoma diagnosis is associated with attenuated tumor volume, performance status decline, and development of sarcopenic adiposity at recurrence

Cohort study of 201 peopleExercise

The Journal of Applied Laboratory MedicineAug 15

Differential NADP-Dependent Isocitrate Dehydrogenases Expression in Metabolically Healthy Obesity vs Metabolic Syndrome: A Probable Predictive Biomarker for Metabolic Deterioration

Case-control study of 120 peopleMetabolic syndrome

Cell ReportsJun 26

Identifying the target, mechanism, and agonist of α-ketoglutaric acid in delaying mesenchymal stem cell senescence

Experiments in miceInterventions

AutophagyJun 26

Mitochondrial protein nmd regulates lipophagy and general autophagy during development

Experiments in fliesAutophagy

Nucleic Acids ResearchJun 11

R-2-hydroxyglutarate-mediated inhibition of KDM4A compromises telomere integrity

Experiments in human cellsTelomerase and telomere maintenance

NeoplasiaDec 27

High p16INK4A expression in glioblastoma is associated with senescence phenotype and better prognosis

Cohort study in peopleSenescence-associated secretory phenotype (SASP)

FASEB JournalMay 23

Isocitrate dehydrogenase 1 upregulation in urinary extracellular vesicles from proximal tubules of type 2 diabetic rats

Experiments in ratsBiomarkers

Advanced BiologyMay 8

The ICL1 and MLS1 Genes, Integral to the Glyoxylate Cycle, are Essential and Specific for Caloric Restriction-Mediated Extension of Lifespan in Budding Yeast

Experiments in yeastMechanisms