IL-6 release

1 paper1 finding

Animals1

Interventions

1

SRT1720

downin human cells1

1 study

SRT1720 decreases IL-6 release in human cells.
“Pharmacological activation of Sirt1 with SRT1720 decreased LPS- and K. pneumoniae-induced IL-6 release in primary human monocytes”
CellsLPS- and K. pneumoniae-induced activationprimary human monocyte
The Sirt1 Activator SRT1720 Mitigates Human Monocyte Activation and Improves Outcome During Gram-Negative Pneumosepsis in Mice
International journal of molecular sciences24 Sep 2025

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International Journal of Molecular Sciences24 Sep

The Sirt1 Activator SRT1720 Mitigates Human Monocyte Activation and Improves Outcome During Gram-Negative Pneumosepsis in Mice

Experiments in miceInterventions