Mitochondrial DNA Part A, DNA Mapping, Sequencing, and Analysis
Comparative mitogenomics of the eulipotyphlan species (Mammalia, Eulipotyphla) provides novel insights into the molecular evolution of hibernation
Computational studyMechanisms
Papers on hedgehog
116 papers3 new in 30 days
Thursday, September 11
Friday, August 8
Thursday, May 8
American Journal of Transplantation
Frailty in lung transplant recipients is associated with anemia and telomere dysfunction but independent of epigenetic age
Case-control study of 43 peopleBiomarkers
Wednesday, May 7
Science Advances
Hedgehog-interacting protein orchestrates alveologenesis and protects against bronchopulmonary dysplasia and emphysema
Experiments in miceEmphysema
Saturday, April 12
The EMBO Journal
Fibroblast hierarchy dynamics during mammary gland morphogenesis and tumorigenesis
Experiments in 45,000 miceMechanisms
Friday, March 28
The Journal of Experimental Medicine
Breast cancer gene-1 (BRCA1) potentiates maladaptive repair after kidney injury
Experiments in miceBRCA1
Sunday, February 16
Nature Communications
Identification of Meibomian gland stem cell populations and mechanisms of aging
Experiments in miceMechanisms
Monday, January 6
FASEB Journal
Klotho mutation does not accelerate intervertebral disc aging in mice
Experiments in miceKL
Translational Research
Canagliflozin inhibits hedgehog interacting protein (Hhip) induction of tubulopathy in diabetic Akita mice
Experiments in miceSGLT2 inhibitors
Wednesday, December 11
Journal of Cellular Physiology
Regulation of the Cilia as a Potential Treatment for Senescence and Tumors: A Review
ReviewCellular senescence
Wednesday, November 27
Wednesday, November 13
Ageing Research Reviews
Epithelial-mesenchymal transition to mitigate age-related progression in lung cancer
ReviewLung
Tuesday, November 5
Monday, November 4
Food Science and Biotechnology
Molecular mechanism of skeletal muscle loss and its prevention by natural resources
ReviewMuscle
Wednesday, October 30
Advanced Science
Cathepsin K-Positive Cell Lineage Promotes In Situ Dentin Formation Controlled by Nociceptive Sonic Hedgehog
Experiments in miceInterventions
Wednesday, October 9
Nature Communications
A germline-to-soma signal triggers an age-related decline of mitochondrial stress response
Experiments in wormsMitochondrial unfolded protein response
Saturday, August 31
Journal of Bone and Mineral Metabolism
Enpp1 mutations promote upregulation of hedgehog signaling in heterotopic ossification with aging
Experiments in miceMechanisms
Tuesday, August 27
The Journal of Clinical Investigation
The senescence-associated secretome of Hedgehog-deficient hepatocytes drives MASLD progression
Study in peopleCellular senescence
Monday, July 22
International Immunopharmacology
Interleukin 25 promotes muscle regeneration in sarcopenia by regulating macrophage-mediated Sonic Hedgehog signaling
Experiments in miceSarcopenia
Thursday, June 27
American Journal of Respiratory and Critical Care Medicine
Dysanapsis Genetic Risk Predicts Lung Function Across the Lifespan
Genetic association study of 369,157 peopleLung
Wednesday, June 5
Crop Health
Transcriptomic alterations in host parasitoid wasps resulting in extended lifespan due to PpNSRV-1 infection
Experiments in model organismsMechanisms
Wednesday, April 10
Journal of Orthopaedic Translation
RPL35 downregulated by mechanical overloading promotes chondrocyte senescence and osteoarthritis development via Hedgehog-Gli1 signaling
Experiments in miceCellular senescence
Thursday, March 14
Friday, February 9
Friday, January 12
Journal of Bone and Mineral Research
Femoral neck width genetic risk score is a novel independent risk factor for hip fractures
Cohort study of 338,742 peopleGenetic risk score
Monday, December 11
Thursday, August 31
Thursday, August 10
Journal of Cachexia, Sarcopenia and Muscle
Cdon ablation in motor neurons causes age-related motor neuron degeneration and impaired sciatic nerve repair
Experiments in miceMechanisms
Monday, June 19
Saturday, April 29
Nature Aging
piRNAs regulate a Hedgehog germline-to-soma pro-aging signal
Experiments in model organismsMechanisms