HDL2 cholesterol

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Obicetrapib

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Obicetrapib increases HDL2 cholesterol in humans.
“In specific analyses of the low-dose group, obicetrapib also raised HDL2 cholesterol, apoA1, S1P, apoM, and apoE.”
Human trialJapanese participants, low-dose groupplasma2.5 mg/d8 weeksn = 12
Cholesteryl ester transfer protein (CETP) inhibition and high-density lipoprotein particle composition: consequences for atherogenesis and neurodegeneration
Scientific reports16 Oct 2026

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Cholesteryl ester transfer protein (CETP) inhibition and high-density lipoprotein particle composition: consequences for atherogenesis and neurodegeneration

Non-randomised trial in 13 peopleInterventions