HDL-fraction lipophilic antioxidants

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Obicetrapib

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Obicetrapib increases HDL-fraction lipophilic antioxidants in humans.
“Obicetrapib robustly increased all antioxidant levels in the HDL fraction”
Human trialJapanese participants; n = 12 per groupplasma2.5, 5, and 10 mg/d8 weeksn = 12
Cholesteryl ester transfer protein (CETP) inhibition and high-density lipoprotein particle composition: consequences for atherogenesis and neurodegeneration
Scientific reports16 Oct 2026

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Cholesteryl ester transfer protein (CETP) inhibition and high-density lipoprotein particle composition: consequences for atherogenesis and neurodegeneration

Non-randomised trial in 13 peopleInterventions