H3K4me1

1 paper

Humans1

Latest

2 in 12 months

bioRxiv27 Jul

Genome-wide multi-layered epigenomic profiling across human aging

Preprint: cross-sectional study of 120 peopleMechanisms

Theranostics8 Dec

Super-enhancer-driven core transcription factor FOXP1 delays endothelial cell senescence via phase separation-mediated SESN3 activation

Experiments in animalsCellular senescence

Nature Communications22 Feb

EccDNA atlas in male mice reveals features protecting genes against transcription-induced eccDNA formation

Experiments in animalsMechanisms

Experimental Cell Research28 Sep

Exercise training alleviates cholesterol and lipid accumulation in mice with non-alcoholic steatohepatitis: Reduction of KMT2D-mediated histone methylation of IDI1

Trial in peopleInterventions

Nature Aging2 Aug

Altered Chromatin States Drive Cryptic Transcription in Aging Mammalian Stem Cells

Experiments in cellsMechanisms

Cancer Discovery13 May

Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia

Study in peopleEpigenetic regulation of gene expression