Grey matter atrophy

Biomarker

2 papers1 finding

  • Humans1

Effects

1

Cerebrovascular reactivity

mediatesin humans1

1 study
  1. Grey matter atrophy mediates cerebrovascular reactivity in humans (55.9%, 56.6% and 79.2% mediated).

    “Regional GM atrophy partially mediated age-related CVR increases in the right frontal pole (P = .004) and fusiform/lingual gyrus (P = .001), as well as age-related CVR reduction”

    Humansin right frontal pole, fusiform/lingual gyrus, and brainstem/cerebellar vermisbrain

    Age-related alterations in regional cerebrovascular reactivity: mediation by grey matter atrophy and association with cognitive performance

    Age and ageing28 Nov 2025

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