Glycolytic and lipogenic gene expression

Biomarker

1 paper1 finding

  • Animals1

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1

ARNTL

downin mice1

1 study
  1. ARNTL decreases glycolytic and lipogenic gene expression in mice.

    “BMAL1 deficiency induces a shift in metabolic gene expression profiles characterized by upregulation of glycolytic and lipogenic gene programs”

    Animalsshown by brown adipocyte-specific BMAL1 knockoutthoracic and abdominal aortic perivascular adipose tissue

    Loss of body-clock protein linked to more artery plaques in mice

    Cells30 Sep 2026

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Cells

Loss of body-clock protein linked to more artery plaques in mice

Experiments linked deletion of a body-clock protein in brown fat cells to greater plaque formation in aging and young mice genetically prone to artery disease.Experiments linked deletion of a body-clock protein in brown fat cells to greater plaque formation in aging and young mice genetically prone to artery disease.

Experiments in miceMechanisms