A cross-sectional analysis of 59,269 UK Biobank participants found different metabolic associations depending on how fat-free mass was measured and fat around organs.A cross-sectional analysis of 59,269 UK Biobank participants found different metabolic associations depending on how fat-free mass was measured and fat around organs.
Genetically higher SHBG increased lumbar fracture risk with an odds ratio of 1.201 in FinnGen and 1.005 in UK Biobank, mediated primarily by bone density.Genetically higher SHBG increased lumbar fracture risk with an odds ratio of 1.201 in FinnGen and 1.005 in UK Biobank, mediated primarily by bone density.
The peptide suppressed inflammation and microglial senescence in mouse models, acting through an autophagy-related signaling pathway.The peptide suppressed inflammation and microglial senescence in mouse models, acting through an autophagy-related signaling pathway.